GTF2IRD1 polyclonal antibody
产品名称: GTF2IRD1 polyclonal antibody
英文名称: GTF2IRD1 polyclonal antibody
产品编号: PAB7077
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of GTF2IRD1.
- Immunogen:
- A synthetic peptide corresponding to human GTF2IRD1.
- Sequence:
- C-NKFTKDTTKLEPAS
- Host:
- Goat
- Theoretical MW (kDa):
- 106
- Specificity:
- This antibody is expected to recognize both reported isoforms (NP_057412.1 and NP_005676.2).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- GTF2IRD1 in craniofacial development of humans and mice.
Tassabehji M, Hammond P, Karmiloff-Smith A, Thompson P, Thorgeirsson SS, Durkin ME, Popescu NC, Hutton T, Metcalfe K, Rucka A, Stewart H, Read AP, Maconochie M, Donnai D.Science. 2005 Nov 18;310(5751):1184-7. Epub 2005 Nov 3.
- Application Image
- ELISA
- Entrez GeneID:
- 9569
- Protein Accession#:
- NP_057412.1;NP_005676.2
- Gene Name:
- GTF2IRD1
- Gene Alias:
- BEN,CREAM1,GTF3,MUSTRD1,RBAP2,WBS,WBSCR11,WBSCR12,hMusTRD1alpha1
- Gene Description:
- GTF2I repeat domain containing 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants. [provided by RefSeq
- Other Designations:
- GTF2I repeat domain-containing 1,Williams-Beuren syndrome chromosome region 11,binding factor for early enhancer,general transcription factor 3,muscle TFII-I repeat domain-containing protein 1 alpha 1
- Gene Pathway
- Related Disease